生物专业PS一.

　　In May, 2003, the power of science dawned on us to drive away the terror of SARS shrouding our souls. Many professors in our college have been commended by the national top officials because of their leading discovery of Multi-Antigenic medicine against the SARS. Seeing the weary faces of these scientific workers, I, a student who loves biology, couldn’t help outpouring my admiration to them because I hoping that someday I will become one of them. My dream of devoting myself into the Scientific Research is becoming clearer and clearer. The classmate around me reading out what I thought, I presented him with an understanding smile.

　　The interest in biology is directly bound to my experience. I used to visit a famous herbalist doctor for my weakness when I was just a kid. He tried to persuade me to become a doctor every time I went there. Oddly enough, although I felt it boring to be a doctor, I became magically interested in the Ancient Chinese Secret, especially an article about westernizing the names of Chinese Medicine written by the herbalist doctor, which activated my idea of combining the Chinese traditional medicine with the modern biological technology. However, it was in senior grade 1 that I really got acquainted with the field of biological science, because I knew from newspaper that a couple graduated from Biological Science College of Wuhan University was running a biological produce company in our city after finishing their study in America. It was rare to see such a thing in my hometown at that time, particularly in the field of biological science, which inspired me a lot. Soon after that, I began my study in this field by reading the related books, which became my first choice after the College Entrance Exam.

　　Finally, my good mark enabled me to enter the Biological Science Department of Wuhan University, which I was longing for. It was in the class which is only open to the excellent students that I finished my four years’ undergraduate study. Deepened by the four-year study there, my grasping to the subject pushed me out of the superficial interest to the enthusiasm in this field and presented me with the high score of GPA 3.68/4.0 on the specialty courses, thanks to my great forts. Besides, taking advantage of the large amount of reading after class, I did a good job on seminar and presentation. Once when I prepared to do the presentation on molecular experimental class, as the chi, I got to collect large amount of files with original topics on “Systematic Evolution of Ligands by Exponential Enrichment (SELEX)” in a very short time. Our group therore got the praise. In addition, as a rare undergraduate, I usually attended the lectures given by the foreign experts invited by our college, which are actually the required courses for post graduates. Not understand much of it as I did, I can acquaint myself with the leading world science and the fective methods in their study, which, I believe, can be helpful for my study in future.

　　In the second year in University, my two schoolmates and I designed an experiment on “study in the anti-epiphyte function of natural ingredients in Huatuo Cream” with a successful application to be an extracurricular study program and got the foundation for experiment. I am the chi of the study group. By using the animalcule experimental technology, we have, on one hand, confirmed the better methods of MIC of camphor (one of the natural ingredients) and on the other, ascertained that calyx canthus oil (another natural ingredient) can work through immunity adjusting rather than anti-epiphyte. In this experiment, my capability of applying what I have learnt into practice and looking up in the literature was greatly improved, my potential was dug out and my final occupation of lying on the scientific research field was set.

　　My solid foundation of this field and potential finally presented me with an opportunity to attend a scientific research program in the following days. Since April, 2005, I have attended many programs in the enzymology lab as the RA of Professor Zou Guolin. In the subject of synthesis of conducting polyaniline by the biocatalyzing of simulation enzyme, I compared the functions of different templates of polyelectrolyte, micelle and mixed micelle and confirmed the most suitable templates for High-pH polyelectrolyte and anion surface-active agent micelle. In the program of “Hemoglobin-biocatalyzed synthesis of conducting molecular complex of polyaniline and lignosulfonate”, I am mainly in charge of the synthesis part as well as attending the enactment of the experimental approach. After comparing the catalysis of Hemoglobin protein, chloridized Hemoglobin and Ferric Chloride, I found the Hb is the best. By studying the inactivation influence of various pH to Hb, I confirmed the most suitable pH, template thickness, aniline thickness, perhydrol thickness and reactivity time for Hb catalyzing reactivity, and synthesized the conducting polyanilin for the following character identification with this suitable conditions (such as the composing of chemical elements, conductivity, heat stability etc) in contrast with the traditional methods in the literature. I also contributed the thesis as the second author in this program.

　　The final success shaded all the difficulties I have ever tasted during the process, leaving the valuable experience. Taking this program as an example, I have met a number of difficulties, because the main cooperator lt school for his sickness, most of the work has to be done by myself independently. from the former step, (Such as the happiest reactivity pH, bottom thickness, reactivity time etc.) which required me to master the theory of the experiment and learn to analyze the experimental data as quick as possible bore setting off to the next step. We need to analyze the reason whether lies in the experimental steps or in the operation in case of problems or errors. For example, when synthesizing the Hb into PANI conductive polyanilin, I found the ideal value of pH in the reactivity is 2.0, which roused my suspicion why the Hemoglobin protein, as a natural protein, can be so active in such a low pH environment. I repeated the experiment several times with carully operating. After eliminating every possibility to the error, I looked up large amount of related files and discussed with my supervisor. It is estimated that the template LGS was synthesizing the H+, which reduced the thickness of H+ in the liquor, e.g. the pH value in the liquor around the template must be higher than 2.0. My estimation was finally proved by measuring the liquor around the template, whose pH goes really between the 4.5 and 5.5, the required range mentioned in the literature. The later experiments with other catalyzer and templates synthesizing PANI were carried out in the higher-pH environment. some of them have been completed while others are still in hand, providing me with more and more theoretical guidance and practical experience.

　　As an excellent student, I am also a good basketball player apart from my good mark. I have participated in the Hubei Female College-student basketball match and got the top. From these extracurricular activities, I realized the importance of the teamwork spirit.

　　I have had solid foundation in biology through the study in Wuhan University, while I realized the big gap between China and the world leaders in this field. So I determined to accept the further education abroad in order to contribute myself in the development of the domestic related enterprises, which is the only way achieve my kid dream. Meanwhile, the study in postgraduate program is critical for my future development, it is therore very important to select a good university to continue my study. Your university is a world famous institution for higher learning with advanced equipments for scientific research, strong faculty and a good academic atmosphere, which play the critical role in the motivation of my potential. So I take your university as my first choice. My solid academic foundation, independent research ability and strong background in biological chemical industry and related subjects, coupled with my determination and strong sense of responsibility, have paved the way for me to undertake advanced studies at an institution of higher learning like yours.

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